Systane Complete versus Systane Hydration PF

Key Features

Systane Complete and Systane Hydration PF are both manufactured by Alcon Inc., a renowned company in the field of eye care. While Systane Complete made its debut in November 2018, Systane Hydration PF entered the market later in March 2020. Systane Complete boasts Nano-Droplet Technology, aimed at enhancing its effectiveness in lubricating and moisturizing the eyes. In contrast, Systane Hydration PF prides itself on being preservative-free and incorporates HydroBoost Technology for prolonged hydration.

Active Ingredients

The active ingredients in each product differ slightly. Systane Complete contains propylene glycol at 0.6%, whereas Systane Hydration PF includes polyethylene glycol 400 at 0.4% alongside propylene glycol at 0.3%. Polyethylene glycol 400 (PEG 400) acts as a lubricant and moisturizer, while propylene glycol serves as a humectant, both relieving dryness and discomfort. Together, they maintain eye moisture balance, enhancing comfort and clarity of vision.

It's important to note that the concentration of PEG 400, propylene glycol, polyethylene glycol 400, along with other ingredients, is carefully balanced to ensure both efficacy and safety in the product. It's best to consult with a pharmacist or your eye doctor before using products containing these ingredients.

Packaging, Pricing and Cost

In terms of packaging, Systane Complete offers a 0.33 oz (10ml) bottle, while Systane Hydration PF comes in the form of 30 vials, each containing 0.7ml (0.02 oz). This is particular convenient when you are on-the-go or travelling. Price ranges also vary; Systane Complete is priced between $13 to $17 for a single 0.33 oz bottle, whereas Systane Hydration PF is priced between $17 to $22 per 30-pack.

When considering the cost per ounce (30ml) or per vial (0.7ml), Systane Complete ranges from $39 to $51 per ounce ($1.30 to $1.70 per ml), whereas Systane Hydration PF comes in at $0.57 to $0.73 per vial ($0.81 to $1.05 per ml).

Systane Complete and Systane Hydration PF - Side-by-Side Specs

Systane Complete

Systane Hydration PF

Product Image Systane Complete Systane Hydration PF
Product Name Systane® Complete Systane® Hydration PF
Type Lubricant Eye Drops Lubricant Eye Drops
Manufacturer Alcon Inc. Alcon Inc.
Release Date Nov 2018 March 2020
FDA Device Class II II
Over the Counter (OTC) Yes Yes
Special Features
  • Nano-Droplet Technology
  • Preservative-free
  • HydroBoost Technology
Active Ingredients
  • Propylene glycol 0.6%
  • Polyethylene glycol 400 0.4%
  • Propylene glycol 0.3%
Wettings Agents, Lubricants, Disinfectants
  • Boric acid
  • Dimyristoyl phosphatidylglycerol
  • Disodium EDTA
  • Hydroxypropyl guar
  • Mineral oil
  • Polyoxl 40 stearate
  • Polyquaternium-1 - POLYQUAD® 0.001%
  • Sorbitan tristearate
  • Sorbitol
  • Aminomethyl propanol
  • Boric acid
  • Hydroxypropyl guar
  • Sodium hyaluronate
  • Sorbitol
Aqueous Base with:
  • Hydrochloric acid
  • Sodium hydroxide
  • Hydrochloric acid
  • Potassium chloride
  • Sodium borate
  • Sodium chloride
  • Sodium hydroxide
Packaging, Pricing and Offers
Packaging Details 0.33 oz (10ml) 30 vials 0.7ml (0.02 oz)
Price Range $13 - $17 (1 x 0.33 oz) $17 - $22 per 30-pack
Cost per ounce (30ml) $39 - $51 per oz
(= $1.30 - $1.70 per ml)
$0.57 - $0.73 per vial
(= $0.81 - $1.05 per ml)
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