With so many contact lens cleaning and multi-purpose solutions on the market, it is difficult to find the right one. We have looked at some of the popular solutions. These lens solutions have been tested on patients wearing ACUVUE OASYS® contact lenses.

Clear Care (Novartis / CIBA Vision) - H2O based

Clear Care

  • Effective disinfecting system for simultaneous cleaning & daily protein removal.
  • Kills germs and bacteria that can cause serious infections. Neutralizes the active disinfectant to create a gentle saline solution.

  • For all soft and RGP lenses such as ACUVUE® OASYS.

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Opti-Free Express (Alcon) - PolyQuad

Opti-Free Express

  • One box containing two 12-ounce bottles of contact lens cleaning solution (24 total ounces)

  • Cleans, rinses, disinfects, and stores any soft contact lenses such as ACUVUE OASYS® while moisturizing for comfort

  • Removes protein; no separate enzyme required when used daily. Easy-to-use; no rubbing required

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Renu MultiPlus (Bausch & Lomb) - Biguanides

Renu MultiPlus

  • Cleans, rinses, disinfects, stores soft contacts (such as ACUVUE® OASYS)

  • Hydranate Daily Protein Remover removes protein deposits that accumulate during wear

  • No separate enzyme cleaner required

  • 100% satisfaction guaranteed

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Renu MultiPupose (Bausch & Lomb) - Biguanides

Renu MultiPurpose

  • Cleans, rinses, disinfects, stores soft contact lenses (such as ACUVUE® OASYS)

  • Hydranate Daily Protein Remover removes protein deposits that accumulate during wear. No separate enzyme cleaner required

  • Larger Size! - 16 oz - Multi Pack - 32 oz Total (473 ml)

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Complete MPS Easy Rub (AMO) - Biguanides

Complete MultiPurpose Easy Rub

  • Easy Rub Formula!
  • 2x 16 oz Bottles, VALUE PACK!

  • For Soft Contact Lenses such as ACUVUE® OASYS

  • Cleans, Rinses, Stores, Disinfects, Removes Protein

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Aquify (Novartis) - Biguanides

Aquify MultiPurpose

  • Ideal for silicone hydrogel lenses. Specially formulated to reduce lens case contamination.

  • Cleans, disinfects & moisturizes in 5 minutes - 5 minutes with rub.

  • Cleans. Rinses. Disinfects. Stores. For soft - hydrophilic - contact lenses (such as ACUVUE® OASYS).

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Unisol Saline (Alcon) - Saline Based


  • For rinsing after cleaning and for heat disinfection of soft (hydrophilic) contact lenses such as ACUVUE® OASYS

  • Sterile and preservative-free saline solution

  • pH-balanced to eye's natural tears for superior comfort

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Note: Always consult your eye care professional before buying and read the product label and product instructions.


User Comments

Alcon Solution

 "I am currently using the Alcon Opti-Clean solution and I love it. My lenses don't dry out too often; I leave them in all day without putting any eye drops in them and it doesn't feel uncomfortable. There's no rubbing required which makes it easier to clean your lenses. Best solution out there!"

Posted by: Megan

Opti Free Replenish use with ACUVUE OASYS® lenses

"I started to experience an almost conjuncitivitis like infection. Watery eyes/ blurry vision/ VERY DRY and splitting of corners of eyes. Spoke with my Dr. and was told they have been hearing many similar stories from other patients. I was told to discontinue use of Opti-Free Replenish.

Posted by: Sara Akins

"Sara- Interesting!! I have been using that same solution and have been having some problems for about the last 2 months. I wish my doctor would have considered this possibility because I have been wearing my glasses for a month. I will change my contact solution and see if that helps. Thanks for sharing. Maybe they changes the ingredients? 

Does anyone know if we can use the RE-NU sensitivity solution?